Medical Assistants Salary in South Carolina

Medical Assistants in South Carolina have a median of $41,160 a year, below the national $45,690 (−10%); the state ranks 37th of 51 states by median. That is 11% less than the median across all occupations in South Carolina ($46,490). Every neighbouring state pays more: North Carolina and Georgia range from $41,600 in Georgia to $45,140 in North Carolina. South Carolina employs 12,110 medical assistants, 5.25 per 1,000 jobs, the 25th largest count of any state. A location quotient of 1.00 is close to the national share.

South Carolina vs the United States, May 2025

Medical Assistants: wage percentiles, mean, employment, jobs per 1,000 and location quotient in South Carolina and nationally, May 2025
AreaBasisPercentile wageMeanEmploymentJobs per 1,000Location quotient
10th25thMedian75th90th
South CarolinaHourly$16.70$17.93$19.79$22.57$23.61$20.3612,1105.261.00
Annual$34,730$37,290$41,160$46,950$49,110$42,340
United StatesHourly$17.33$18.50$21.97$23.65$28.52$22.17817,870––
Annual$36,050$38,470$45,690$49,180$59,310$46,120
$0$20k$40k$60k10th10th: $34,730$34,73025th25th: $37,290$37,290MedianMedian: $41,160$41,16075th75th: $46,950$46,95090th90th: $49,110$49,110US median
South Carolina annual wage at the 10th, 25th, 50th (median), 75th and 90th percentiles; the line marks the US median. The same numbers are in the table above.
Rank by median
37th of 51 states
Rank by employment
25th of 51 states
Location quotient
1.00
Jobs per 1,000
5.26

Ranks count the 50 states and DC with a published value. The location quotient is the occupation's share of South Carolina's employment divided by its national share; 1.00 means the same share as the nation. Take-home pay at these wages: FastCalc's take-home pay calculator.

Metropolitan areas in South Carolina

10 metropolitan areas and 3 nonmetropolitan areas touching South Carolina publish a row for medical assistants, sorted by median. Areas crossing a state line are listed under every state they touch; a linked metro has its own profile.

AreaMedian hourlyMedian annual10th pct (annual)90th pct (annual)EmploymentJobs per 1,000Location quotient
Charlotte-Concord-Gastonia, NC-SC$22.36$46,520$36,620$56,8406,0604.460.85
Charleston-North Charleston, SC$21.92$45,600$35,970$49,3902,3205.891.12
Greenville-Anderson-Greer, SC$21.57$44,860$34,830$49,1302,5505.871.12
Hilton Head Island-Bluffton-Port Royal, SC$20.97$43,610$35,710$54,6605606.801.29
Spartanburg, SC$19.68$40,930$36,570$48,3806203.750.71
Sumter, SC$19.61$40,780$30,850$47,5901704.870.93
Columbia, SC$19.56$40,680$35,410$47,5402,1905.551.06
Myrtle Beach-Conway-North Myrtle Beach, SC$18.73$38,950$34,290$47,6409106.241.19
Florence, SC$18.65$38,790$33,920$48,0704204.680.89
Augusta-Richmond County, GA-SC$18.50$38,470$32,130$48,4301,6206.981.33
Northwestern South Carolina nonmetropolitan area$18.19$37,830$33,300$53,1604404.710.89
Northeastern South Carolina nonmetropolitan area$18.07$37,580$31,640$47,8303804.890.93
Southern South Carolina nonmetropolitan area$17.61$36,630$29,710$46,7201803.430.65

Neighbouring states

StateMedian hourlyMedian annualEmploymentLocation quotient
South Carolina$19.79$41,16012,1101.00
Georgia$20.00$41,60028,7801.12
North Carolina$21.70$45,14023,6500.91

See the national page for Medical Assistants (every state ranked) and the South Carolina wage profile (every occupation in the state).

Source and notes

Data: BLS OEWS May 2025, released 2026-05-15. Cross-industry estimates, all ownerships. BLS page: OEWS South Carolina estimates.

  • Annual wages assume 2,080 hours a year at the hourly rate; occupations BLS publishes on one basis only show an en dash (–) on the other.
  • Employment is rounded to the nearest 10 by BLS. Where BLS withholds a cell, nothing is estimated in its place.